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產(chǎn)品編號(hào) bs-1904R
英文名稱(chēng) Rabbit Anti-Syndecan 2  antibody
中文名稱(chēng) 多配體蛋白聚糖2抗體抗體
別    名 CD362; CD 362; Fibroglycan; Heparan sulfate proteoglycan core protein; HSPG; SDC2; SDC2_HUMAN; SYND2; Syndecan-2.  硫酸乙酰肝素蛋白多糖核心蛋白;
Specific References  (1)     |     bs-1904R has been referenced in 1 publications.
[IF=2.97] Hambruch, N., et al. "Bovine placentomal heparanase and syndecan expression is related to placental maturation." Placenta.  IHC-P ;  Bovine.  
研究領(lǐng)域 細(xì)胞粘附分子  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human,Mouse,Rat,Cow (predicted: Pig,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 20kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Syndecan-2: 101-201/201 <Cytoplasmic>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq].

Function:
Cell surface proteoglycan that bears heparan sulfate.

Subcellular Location:
Plasma membrane (Type I membrane protein)

Similarity:
Belongs to the syndecan proteoglycan family.

SWISS:
P34741

Gene ID:
6383

Database links:

Entrez Gene: 374102 Chicken

Entrez Gene: 615785 Cow

Entrez Gene: 6383 Human

Entrez Gene: 15529 Mouse

Entrez Gene: 25615 Rat

Omim: 142460 Human

SwissProt: Q58DD4 Cow

SwissProt: P34741 Human

SwissProt: P43407 Mouse

SwissProt: P34900 Rat

Unigene: 1501 Human

Unigene: 598247 Human

Unigene: 234266 Mouse

Unigene: 11127 Rat



產(chǎn)品圖片
Sample: K562(Human) Cell Lysate at 30 ug Primary: Anti-heparin sulphate protoglycans 1 ?(bs-1904R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 20 kD Observed band size: 24 kD
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